Anti-MEF2B Antikörper [PCRP-MEF2B-2F9] (A278112)

Name: Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free
Brand: Antibodies.com
SKU: A278112
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [PCRP-MEF2B-2F9] Maus Antikörper gegen MEF2B für IP, WB, Flow Cytometry und IF.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

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Stichworte:

Monospezifischer Antikörper

Produktdetails

Produktname

Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free

Beschreibung

Mouse monoclonal [PCRP-MEF2B-2F9] antibody to MEF2B.

Spezifität

The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

Anwendungen

IP, WB, Flow Cytometry, IF

Verdünnungen

IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant full-length human MEF2B protein.

Wirt

Mouse

Klonalität

Monoclonal

Klon

PCRP-MEF2B-2F9

Isotyp

IgG2a

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

1 mg/ml

Molekulargewicht

160 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] (A277524).

Synonyme

MADS box transcription enhancer factor 2, MDS1 EVI1, MEF2B_HUMAN, Myocyte enhancer factor 2B, Myocyte specific enhancer factor 2B, Myocyte-specific enhancer factor 2B, PRDM3, RSRFR2, Serum response factor like protein 2, Serum response factor-like protein 2, XMEF2

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (3)

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Figure 1: Flow Cytometry - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free (A278112)

Flow cytometric analysis of PFA-fixed HeLa cells using Anti-MEF2B Antibody [PCRP-MEF2B-2F9] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Unstained cells (Red).

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Figure 2: Immunofluorescence - Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free (A278112)

Immunofluorescent analysis of PFA-fixed HeLa cells stained with Anti-MEF2B Antibody [PCRP-MEF2B-2F9] followed by Goat Anti-Mouse IgG (CF® 488) (Green). CF® 640A Phalloidin (Red).

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Figure 3: Anti-MEF2B Antibody [PCRP-MEF2B-2F9] - BSA and Azide free (A278112)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-MEF2B Antibody [PCRP-MEF2B-2F9]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.