Anti-MCM3 Antikörper [MCM3/6706] (A315288)

Anti-MCM3 Antibody [MCM3/6706]

Mouse monoclonal [MCM3/6706] antibody to MCM3.

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

IHC-P

MCF-7, Jurkat or Ramos cells. Human colon or tonsil.

IHC: 1-2 µg/ml

Human

Recombinant fragment (aa 650-750) of human MCM3 protein. The exact sequence is proprietary.

Mouse

Monoclonal

MCM3/6706

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

115 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, DNA polymerase alpha holoenzyme associated protein P1, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, DNA replication licensing factor mcm3, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, MCM3 minichromosome maintenance deficient 3, MCM3_HUMAN, MGC1157, Minichromosome maintenance complex component 3, Minichromosome maintenance deficient 3, Minichromosome maintenance protein 3, P1 h, P1 MCM3, P1 Protein, P1-MCM3, P1.h, p102, P102 protein, Replication licensing factor beta subunit, RLF beta subunit, RLF subunit beta, RLFB