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Anti-MAdCAM1 Antikörper [314G8] (A279253)

$145

Monoklonal [314G8] Maus Antikörper gegen MAdCAM1 für IHC-Fr und ELISA.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-MAdCAM1 Antibody [314G8]
Beschreibung
Mouse monoclonal [314G8] antibody to MAdCAM1.
Spezifität
This antibody recognises human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyer's patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
Anwendungen
IHC-Fr, ELISA
Verdünnungen
Flow Cytometry: 1:10 - 1:100, IHC-Fr: 1:25 - 1:200, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reaktivität
Human
Immunogen
Recombinant soluble MAdCAM-1-fc fusion protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
314G8
Isotyp
IgG1
Konjugat

Unconjugated

Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Allgemeine Hinweise
Mouse anti Human MAdCAM-1 antibody, clone 314G8 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyer's patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7 (Leung et al. 2004).
Synonyme
Addressin mucosal, hMAdCAM 1, hMAdCAM-1, MACAM1, MAdCAM 1, MAdCAM-1, MADCA_HUMAN, Mucosal addressin cell adhesion molecule 1, Mucosal vascular addressin cell adhesion molecule 1
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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