Rekombinant Anti-liver FABP Antikörper [rFABP1/8520] (A315259)

Anti-liver FABP Antibody [rFABP1/8520]

Recombinant mouse monoclonal [rFABP1/8520] antibody to liver FABP.

Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

WB, IHC-P

Liver or colon carcinoma tissues (IHC). Human kidney tissue lysate (WB).

WB: 2-4 µg/ml, IHC: 1-2 µg/ml

Human

Human recombinant FABP1 protein fragment (around Amino Acids 1-127). The exact sequence is proprietary.

Mouse

Monoclonal

rFABP1/8520

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

14 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

FABP 1, FABP1, FABPL, FABPL_HUMAN, Fatty Acid Binding Protein, Fatty Acid Binding Protein 1, Fatty acid binding protein 1 liver, Fatty acid-binding protein, Fatty acid-binding protein 1, Fatty acid-binding protein liver, L FABP, L-FABP, liver, Liver-type fatty acid-binding protein