Recombinant Anti-liver FABP Antibody [FABP1/8521R] (A315255)

Anti-liver FABP Antibody [FABP1/8521R]

Recombinant rabbit monoclonal [FABP1/8521R] antibody to liver FABP.

Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Liver or colon carcinoma tissues (IHC). Human kidney tissue lysate (WB).

IHC: 1-2 µg/ml

Human

Human recombinant FABP1 protein fragment (around Amino Acids 1-127). The exact sequence is proprietary.

Rabbit

Monoclonal

FABP1/8521R

kappa

Protein A/G chromatography.

200 µg/ml

14 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

FABPL, Fatty acid-binding protein 1, Fatty acid-binding protein, liver, L-FABP, Liver-type fatty acid-binding protein