Anti-Lambda Light Chain Antikörper [N10/2] (A252177)

Anti-Lambda Light Chain Antibody [N10/2] - BSA and Azide free

Mouse monoclonal [N10/2] antibody to Lambda Light Chain.

This antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Purified IgG from human serum.

Mouse

Monoclonal

N10/2

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

~22.5 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Lambda Light Chain Antibody [N10/2] (A248997).

Bence Jones protein, BJP, Constant region of lambda light chains, Ig lambda chain C regions, ig lambda-6 chain C region, IGLC, IGLC 1, IGLC 2, IGLC 3, IGLC1, IGLC2, IGLC3, IGLC6, IGLV, Immunoglobulin lambda constant 1, Immunoglobulin lambda constant regin 1, immunoglobulin lambda gene cluster, Immunoglobulin lambda locus, Immunoglobulin lambda variable cluster, Immunoglobulin: lambda light chain, Mcg marker, Paraprotein