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Anti-Kallikrein 5 Antikörper [KLK5/3844] (A315198)

$765

Monoklonal [KLK5/3844] Maus Antikörper gegen Kallikrein 5 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Kallikrein 5 Antibody [KLK5/3844]
Beschreibung
Mouse monoclonal [KLK5/3844] antibody to Kallikrein 5.
Spezifität
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is still currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein, or HGK-1 and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers. KLK5 expression is abundant in skin, mammary gland and testis.
Anwendungen
IHC-P
Positivkontrolle
Human skin tissue (IHC). MCF-7 cell lysates.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment of human KLK5 protein (around Amino Acids 36-177). The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
KLK5/3844
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
33 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
HK5, Kallikrein L2, Kallikrein like 2, Kallikrein like protein 2, Kallikrein related peptidase 5, Kallikrein-5, Kallikrein-like protein 2, Kallikrein5, KLK 5, KLK L2, KLK-L2, KLK5, KLK5_HUMAN, KLKL 2, KLKL2, SCTE, Stratum corneum tryptic enzyme, UNQ570/PRO1132
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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