Rabbit polyclonal antibody to JAK2 (phospho Tyr1007).
Spezifität
This antibody recognises janus kinase 2 (JAK2), also known as tyrosine-protein kinase JAK2, when phosphorylated at tyrosine 1007. JAK2 is a non-receptor tyrosine protein kinase involved in stem cell maintenance, haematopoiesis, and inflammation through its involvement in the JAK/STAT signaling pathway.Autophosphorylation of JAK2 at tyrosine 1007 activates JAK2 and the JAK/STAT signaling pathway.
Anwendungen
WB
Verdünnungen
WB: 1:200 - 1:2,000
Reaktivität
Human
Immunogen
Phospho-specific peptide corresponding to residues surrounding Tyr1007 of human JAK2.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
Lot Specific
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.
Lagerung
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti JAK2 (pTyr1007) antibody recognizes janus kinase 2 (JAK2), also known as tyrosine-protein kinase JAK2, when phosphorylated at tyrosine 1007. JAK2 is a non-receptor tyrosine protein kinase involved in stem cell maintenance, haematopoiesis, and inflammation through its involvement in the JAK/STAT signaling pathway.Autophosphorylation of JAK2 at tyrosine 1007 activates JAK2 and the JAK/STAT signaling pathway. (Lucet et al. 2006).
Synonyme
JAK 2, JAK-2, JAK2_HUMAN, Janus Activating Kinase 2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, OTTHUMP00000043260, THCYT3, Tyrosine protein kinase JAK2, Tyrosine-protein kinase JAK2
