This antibody recognises human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. recognises glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Anwendungen

WB, ELISA

Reaktivität

Human

Immunogen

Recombinant full length human IFN Beta, expressed in E.coli.

Wirt

Mouse

Klonalität

Monoclonal

Klon

BB4

Isotyp

IgG2a

Konjugat

Unconjugated

Reinigung

Protein G affinity chromatography of tissue culture supernatant.

Konzentration

1 mg/ml

Produktform

Liquid

Formulierung

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Lagerung

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Allgemeine Hinweise

Mouse anti Human IFN beta antibody, clone BB4 recognizes human interferon beta (IFN Beta), a ~22 kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. Mouse anti Human IFN beta antibody, clone BB4 recognizes glycosylated and non-glycosylated human IFNß and there is no cross-reactivity with human interferon alpha or human interferon gamma.

Synonyme

beta-interferon, Fibroblast interferon, IFB, IFF, IFN beta, IFN-beta, IFNB, IFNB 1, IFNB1, IFNB_HUMAN, Interferon beta 1 fibroblast, Interferon beta precursor, MGC96956

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.