Anti-Interferon alpha Antibody - BSA and Azide free
Beschreibung
Rabbit polyclonal antibody to Interferon alpha.
Spezifität
This antibody recognises chicken Interferon alpha (chIFNa). Similarities exist between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes , chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and acts as a potent antiviral agent. Rabbit anti Chicken interferon alpha antibody (AHP943Z) cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma and in bioassays, Rabbit anti Chicken interferon alpha antibody neutralizes chIFN-alpha, but not chIFN-beta, and can therefore be used to discriminate IFN alpha and IFN beta bioactivities.
Anwendungen
ELISA, Functional Assays, WB, IP
Reaktivität
Chicken
Immunogen
Recombinant Chicken IFN alpha
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
500 µg/ml
Molekulargewicht
Approximately 19 kDa.
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline.
Lagerung
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti Chicken interferon alpha antibody recognizes chicken Interferon alpha (chIFNa). Similarities exist between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes (Sick et al. 1996), chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and acts as a potent antiviral agent (Schwartz et al. 2004).Rabbit anti Chicken interferon alpha antibody (AHP943Z) cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma and in bioassays, Rabbit anti Chicken interferon alpha antibody neutralizes chIFN-alpha, but not chIFN-beta, and can therefore be used to discriminate IFN alpha and IFN beta bioactivities (Schwartz et al. 2004).
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [Research Grade Biosimilar] - Low endotoxin, Azide free (A324113) - Antibodies.com](https://cdn.antibodies.com/image/catalog/324/A324113_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [Research Grade Biosimilar] - Low endotoxin, Azide free (A324114) - Antibodies.com](https://cdn.antibodies.com/image/catalog/324/A324114_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [2-48] (A248916) - Antibodies.com](https://cdn.antibodies.com/image/catalog/248/A248917_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [2-48] - BSA and Azide free (A252096) - Antibodies.com](https://cdn.antibodies.com/image/catalog/252/A252097_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Interferon alpha 1 Antibody [IFNA/6689] (A277653) - Antibodies.com](https://cdn.antibodies.com/image/catalog/277/A277653_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Interferon alpha 1 Antibody [IFNA/6689] - BSA and Azide free (A278241) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278241_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [2-52] (A248917) - Antibodies.com](https://cdn.antibodies.com/image/catalog/248/A248918_1.jpg?profile=product_alternative)
![SDS-PAGE - Anti-Interferon alpha 1 Antibody [2-52] - BSA and Azide free (A252097) - Antibodies.com](https://cdn.antibodies.com/image/catalog/252/A252098_1.jpg?profile=product_alternative)