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Anti-Integrin alpha 2 Antikörper [DX5] (FITC) (A280281)

$420

Monoklonal [DX5] Ratte Antikörper gegen Integrin alpha 2 (FITC) für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Integrin alpha 2 Antibody [DX5] (FITC)
Beschreibung
Rat monoclonal [DX5] antibody to Integrin alpha 2 (FITC).
Spezifität
This antibody recognises mouse CD49b, also known as Very Late Antigen-2 (VLA-2) or alpha-2 integrin. CD49b is a ~160kDa single pass type I membrane protein expressed by NK cells and a small subset of T-cells. Rat anti mouse CD49b, clone DX5 stains NK cells from all mouse strains tested including Balb/c mice. CD49b acts as a receptor for collagen, laminin, fibronectin and E-cadherin.
Anwendungen
Flow Cytometry
Verdünnungen
Use 10µl of the suggested working dilution to label 106 cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).
Reaktivität
Mouse
Immunogen
RIL-2 propagated NK1.1+ cells from C57BL/6 mice.
Wirt
Rat
Klonalität
Monoclonal
Klon
DX5
Isotyp
IgM
Konjugat

FITC

Excitation: 490nm, Emission: 525nm

Konzentration
100 µg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Lagerung
Store undiluted at 4°C only. Do not freeze! This product is photosensitive and should be protected from light. Avoid freeze / thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rat anti Mouse CD49b monoclonal antibody, clone DX5 recognizes mouse CD49b, also known as Very Late Antigen-2 (VLA-2) or alpha-2 integrin. CD49b is a ~160kDa single pass type I membrane protein expressed by NK cells and a small subset of T-cells (Pellicci et al. 2005). Rat anti mouse CD49b, clone DX5 stains NK cells from all mouse strains tested including Balb/c mice (Arese et al. 2001). CD49b acts as a receptor for collagen, laminin, fibronectin and E-cadherin (Carafoli et al. 2013).
Synonyme
BR, CD 49b, CD49 antigen like family member B, CD49 antigen-like family member B, CD49b, CD49b antigen, Collagen receptor, DX5, Glycoprotein Ia deficiency included, GP Ia, GP Ia deficiency, included, GPIa, HPA 5 included, HPA5 included, Human platelet alloantigen system 5, Integrin alpha II, Integrin alpha-2, Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor), ITA2_HUMAN, ITGA2, Platelet alloantigen Br(a), included, Platelet antigen Br, Platelet glycoprotein GPIa, Platelet glycoprotein Ia, Platelet glycoprotein Ia/IIa, Platelet membrane glycoprotein Ia, Platelet receptor for collagen, deficiency of, included, Very late activation protein 2 receptor alpha 2 subunit, VLA 2, VLA 2 alpha chain, VLA 2 subunit alpha, VLA-2 subunit alpha, VLA2, VLA2 receptor alpha 2 subunit, VLAA2
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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