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Anti-IL2 Receptor alpha Antikörper [IL2RA/2395] (A249018)

Monoklonal [IL2RA/2395] Maus Antikörper gegen IL2 Receptor alpha für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-IL2 Receptor alpha Antibody [IL2RA/2395]
Beschreibung
Mouse monoclonal [IL2RA/2395] antibody to IL2 Receptor alpha.
Spezifität
This antibody recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 2-4 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 42-183, of human IL2RA protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
IL2RA/2395
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
55 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-IL2 Receptor alpha Antibody [IL2RA/2395] - BSA and Azide free (A252198).
Synonyme
CD25, CD25 antigen, IDDM10, IL 2 receptor alpha subunit, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2 RA, IL2-RA, IL2R, IL2R, alpha chain, IL2RA, IL2RA_HUMAN, IMD41, Interleukin 2 receptor, Interleukin 2 receptor alpha, Interleukin 2 receptor alpha chain, Interleukin-2 receptor subunit alpha, p55, t-cell growth factor receptor, TAC, TAC antigen, TCGFR
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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