This antibody recognises human Interleukin-21 (IL-21), a cytokine with immunoregulatory activity. IL-21 stimulates B- and T-cell proliferation and increases the activity of NK cells and disease-specific cytotoxic T-cells. It might also inhibit dendritic cell activation and maturation during the T-cell mediated immune response.
Anwendungen
WB, IHC-Fr
Verdünnungen
IHC-Fr: 2 µg/ml, WB: 0.5 - 1 µg/ml
Reaktivität
Human, Rhesus Monkey
Immunogen
A peptide corresponding to 15 amino acids near the centre of human IL-21.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Reinigung
Affinity chromatography.
Konzentration
1 mg/ml
Molekulargewicht
Approximately 18 kDa in HL60 cell lysate.
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Allgemeine Hinweise
Rabbit anti Human Interleukin-21 antibody recognizes human Interleukin-21 (IL-21), a cytokine with immunoregulatory activity. IL-21 stimulates B- and T-cell proliferation and increases the activity of NK cells and disease-specific cytotoxic T-cells. It might also inhibit dendritic cell activation and maturation during the T-cell mediated immune response.