Anti-IL-15 Antikörper [IL15/4353] (A278263)

Name: Anti-IL-15 Antibody [IL15/4353] - BSA and Azide free
Brand: Antibodies.com
SKU: A278263
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [IL15/4353] Maus Antikörper gegen IL-15 für IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

Garantien

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Stichworte:

Monospezifischer Antikörper

Produktdetails

Produktname

Anti-IL-15 Antibody [IL15/4353] - BSA and Azide free

Beschreibung

Mouse monoclonal [IL15/4353] antibody to IL-15.

Spezifität

Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the Î² signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2RÎ³ subunit.

Anwendungen

IHC-P

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant fragment corresponding to human IL-15. The exact sequence is proprietary.

Wirt

Mouse

Klonalität

Monoclonal

Klon

IL15/4353

Isotyp

IgG1

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

1 mg/ml

Molekulargewicht

14-15 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IL-15 Antibody [IL15/4353] (A277675).

Synonyme

IL 15, IL15, IL15_HUMAN, Interleukin 15, Interleukin-15, Interleukin15, MGC9721

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (3)

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Figure 1: Immunohistochemistry - Anti-IL-15 Antibody [IL15/4353] - BSA and Azide free (A278263)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human adrenal gland tissue using Anti-IL-15 Antibody [IL15/4353].

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Figure 2: SDS-PAGE - Anti-IL-15 Antibody [IL15/4353] - BSA and Azide free (A278263)

SDS-PAGE analysis of Anti-IL-15 Antibody [IL15/4353] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 3: Anti-IL-15 Antibody [IL15/4353] - BSA and Azide free (A278263)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-IL-15 Antibody [IL15/4353]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.