Allgemeine Hinweise
Rabbit anti Mouse interleukin-15 antibody, recognizes interleukin-15 (IL-15), a four alpha helix member of the cytokine family of proteins. IL-15 elicits its biological function through a receptor complex composed of IL-2/IL-15 receptor beta. Upon binding of IL-15 to its receptor, the JAK, STAT, PI3K or MAPK signaling pathways can be activated (Robinson & Schluns 2017). This can result in the stimulation of T cell proliferation, generation of cytotoxic T lymphocytes, stimulation of immunoglobulin synthesis by B cells and the generation and persistence of natural killer cells (Steel et al. 2012).