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Anti-ICOS Ligand Antikörper [ICOSL/3260] (A251759)

Monoklonal [ICOSL/3260] Maus Antikörper gegen ICOS Ligand für ELISA und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-ICOS Ligand Antibody [ICOSL/3260] - BSA and Azide free
Beschreibung
Mouse monoclonal [ICOSL/3260] antibody to ICOS Ligand.
Spezifität
This antibody recognizes a protein of 36kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway.
Anwendungen
ELISA, IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 23-149, of human ICOSLG protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
ICOSL/3260
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
36 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ICOS Ligand Antibody [ICOSL/3260] (A248577).
Synonyme
B7 H2, B7 homolog 2, B7 homologue 2, B7 like protein Gl50, B7 related protein 1, B7-H2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP 1, B7RP-1, B7RP1, CD 275, CD275, CD275 antigen, GL 50, GL50, ICOS L, ICOS LG, ICOSL, Icoslg, ICOSL_HUMAN, Inducible T cell co stimulator ligand, KIAA0653, LICOS, Transmembrane protein B7 H2 ICOS ligand
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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