This antibody reacts with CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
Anwendungen
Flow Cytometry, IHC-P, Functional Studies
Verdünnungen
FUNC: This antibody blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1), Flow Cytometry: 1-4 µg/ml, IHC-P: 10 µg/ml; Positive Control: tonsil.
Reaktivität
Human
Immunogen
Leukocytes from a patient suffering from a LGL Type leukemia.
Wirt
Mouse
Klonalität
Monoclonal
Klon
MEM-04
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A chromatography.
Konzentration
1 mg/ml
Geschätztes MW
120-130 kDa
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.