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Anti-ICAM3 Antikörper [101-1D2] (A248909)

Monoklonal [101-1D2] Maus Antikörper gegen ICAM3 für Flow Cytometry, IF und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-ICAM3 Antibody [101-1D2]
Beschreibung
Mouse monoclonal [101-1D2] antibody to ICAM3.
Spezifität
This antibody recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.
Anwendungen
Flow Cytometry, IF, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Stimulated human leukocytes.
Wirt
Mouse
Klonalität
Monoclonal
Klon
101-1D2
Isotyp
IgG2a
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
110-160 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ICAM3 Antibody [101-1D2] - BSA and Azide free (A252089).
Synonyme
CD50, CDW 50, CDw50, ICAM 3, ICAM-3, ICAM-R, ICAM3_HUMAN, ICAMR, Intercellular adhesion molecule 3
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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