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Anti-HLA DRA Antikörper [169-1B5.2] (A248848)

Monoklonal [169-1B5.2] Maus Antikörper gegen HLA DRA für Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-HLA DRA Antibody [169-1B5.2]
Beschreibung
Mouse monoclonal [169-1B5.2] antibody to HLA DRA.
Spezifität
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Anwendungen
Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human, Bovine, Feline
Immunogen
Human peripheral blood leukocytes.
Wirt
Mouse
Klonalität
Monoclonal
Klon
169-1B5.2
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
36 kDa (alpha chain) / 27 kDa (beta chain)
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HLA DRA Antibody [169-1B5.2] - BSA and Azide free (A252028).
Synonyme
DR alpha chain, DR alpha chain precursor, DRA_HUMAN, DRB1, DRB4, Histocompatibility antigen HLA DR alpha, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR alpha chain, HLA DR1B, HLA DR3B, HLA DRA1, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLA-DR, HLA-DRA, HLADR4B, HLADRA1, HLADRB, Major histocompatibility complex class II DR alpha, Major histocompatibility complex class II DR beta 1, Major histocompatibility complex class II DR beta 3, Major histocompatibility complex class II DR beta 4, Major histocompatibility complex class II DR beta 5, MGC117330, MHC cell surface glycoprotein, MHC class II antigen DRA, MHC II, MLRW
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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