This antibody recognises Histone deacetylase 4, also known as HDAC4. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. HDAC4 is a member of class IIa of the histone deacetylases which unlike class I is not found in the only in the nucleus but rather shuttles back and forth between nucleus and cytoplasm.
Anwendungen
WB, IF
Verdünnungen
IF: 1:50 - 1:200, WB: 1:500 - 1:2,000
Reaktivität
Human, Mouse, Rat
Immunogen
Synthetic peptide of human HDAC4.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
Lot Specific
Molekulargewicht
Approximately 119 kDa in cell lysates and tissue lysates under reducing conditions
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Lagerung
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti histone deacetylase 4 antibody recognizes histone deacetylase 4, also known as HDAC4. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. HDAC4 is a member of class IIa of the histone deacetylases which unlike class I is not found in the only in the nucleus but rather shuttles back and forth between nucleus and cytoplasm.
Synonyme
AHO3, BDMR, EC 3.5.1.98, HA6116, HD 4, HD4, HDAC 4, HDAC A, HDAC4_HUMAN, HDACA, Histone deacetylase 4, Histone Deacetylase A, KIAA0288