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Anti-HDAC3 Antikörper [PCRP-HDAC3-2D4] (A278426)

Monoklonal [PCRP-HDAC3-2D4] Maus Antikörper gegen HDAC3 für ELISA, IP, Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-HDAC3 Antibody [PCRP-HDAC3-2D4] - BSA and Azide free
Beschreibung
Mouse monoclonal [PCRP-HDAC3-2D4] antibody to HDAC3.
Spezifität
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.
Anwendungen
ELISA, IP, Flow Cytometry, IF
Verdünnungen
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human HDAC3 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-HDAC3-2D4
Isotyp
IgG2b
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
49 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-HDAC3 Antibody [PCRP-HDAC3-2D4] (A277838).
Synonyme
HD3, HDAC 3, HDAC3_HUMAN, Histone deacetylase 3, RPD3, RPD3 2, RPD3-2, SMAP45
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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