Rabbit polyclonal antibody to GSK3 alpha (phospho Ser21).
Spezifität
This antibody recognises GSK3 alpha when phosphorylated at serine 21. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 alpha is phosphorylated at serine 21 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 alpha at serine 21 leads to inactivation of GSK3 alpha.
Anwendungen
WB
Verdünnungen
WB: 1:500 - 1:2,000
Reaktivität
Human
Immunogen
Phospho-specific peptide corresponding to residues surrounding Ser21 of human GSK3 ALPHA.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
Lot Specific
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Lagerung
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti GSK3 Alpha (pSer21) antibody recognizes GSK3 alpha when phosphorylated at serine 21. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 alpha is phosphorylated at serine 21 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 alpha at serine 21 leads to inactivation of GSK3 alpha.