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Rekombinant Anti-Filaggrin Antikörper [rFLG/1945] (A278474)

Monoklonal [rFLG/1945] Maus Antikörper gegen Filaggrin für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Filaggrin Antibody [rFLG/1945] - BSA and Azide free
Beschreibung
Recombinant mouse monoclonal [rFLG/1945] antibody to Filaggrin.
Spezifität
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Anwendungen
WB, IHC-P
Verdünnungen
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 198-288, of human Filaggrin. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rFLG/1945
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
26-45 kDa (Processed) / 350 kDa (Profilaggrin)
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Filaggrin Antibody [rFLG/1945] (A277886).
Synonyme
ATOD2, Epidermal filaggrin, Filaggrin precursor, FILA_HUMAN, Fillagrin, FLG, Profilaggrin
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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