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Anti-Factor VII Antikörper [F7/3515] (A314948)

$765

Monoklonal [F7/3515] Maus Antikörper gegen Factor VII für ELISA und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Factor VII Antibody [F7/3515]
Beschreibung
Mouse monoclonal [F7/3515] antibody to Factor VII.
Spezifität
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.
Anwendungen
ELISA, IHC-P
Positivkontrolle
Human liver or gastric carcinoma.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (around Amino Acids 366-466) of human F7 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
F7/3515
Isotyp
IgG2
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
200 kDa / 80 kDa / 73 kDa / 50 kDa / 43 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
Cf7, Coagulation factor VII, coagulation factor VII (serum prothrombin conversion accelerator), Eptacog alfa, F7, F7 deficiency, FA7_HUMAN, Factor VII deficiency, Factor VII heavy chain, Factor VII light chain, FVII, FVII coagulation protein, Hypoproconvertinemia, OTTHUMP00000018733, OTTHUMP00000018734, Proconvertin, Serum prothrombin conversion accelerator, SPCA
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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