Mouse monoclonal [SULT1E1/7124] antibody to Estrogen Sulfotransferase.
Spezifität
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Anwendungen
WB, IHC-P
Positivkontrolle
HEPG2 cells. Human liver, intestine or kidney.
Verdünnungen
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (around Amino Acids 100-294) of human SULT1E1 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
SULT1E1/7124
Isotyp
IgG2
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
35 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
EST, EST-1, EST1, estrogen-preferring, estrone sulfotransferase, ST1E1, ST1E1_HUMAN, STE, Sulfotransferase, Sulfotransferase 1E1, Sulfotransferase estrogen preferring, Sulfotransferase family 1E member 1, SULT1E1
![Immunohistochemistry - Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] (A250068) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250068_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] - BSA and Azide free (A253248) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253248_1.jpg?profile=product_alternative)
