Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] - BSA and Azide free
Beschreibung
Mouse monoclonal [CPTC-SULT1E1-1] antibody to Estrogen Sulfotransferase.
Spezifität
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Anwendungen
WB, IHC-P
Verdünnungen
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human SULT1E1 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
CPTC-SULT1E1-1
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
35 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human small intestine using Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1].
SDS-PAGE analysis of Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.