+1 (314) 370-6046 oderKontakt

Anti-EIF2S1 Antikörper [PCRP-EIF2S1-1E2] (A248414)

Monoklonal [PCRP-EIF2S1-1E2] Maus Antikörper gegen EIF2S1 für Flow Cytometry, IF und WB.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-EIF2S1 Antibody [PCRP-EIF2S1-1E2]
Beschreibung
Mouse monoclonal [PCRP-EIF2S1-1E2] antibody to EIF2S1.
Spezifität
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2a, eIF2band eIF2g (eukaryotic translation initiation factor 2 a, band g, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2a, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2a controls the rate of tRNA translation. When eIF2a is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2a is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
Anwendungen
Flow Cytometry, IF, WB
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody is predicted to cross react with Rat and Zebrafish.
Immunogen
Recombinant full-length human EIF2S1 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-EIF2S1-1E2
Isotyp
IgG1
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
36 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-EIF2S1 Antibody [PCRP-EIF2S1-1E2] - BSA and Azide free (A251596).
Synonyme
EIF 2, EIF 2 alpha, EIF 2A, EIF 2alpha, eIF-2-alpha, eIF-2A, EIF-2alpha, EIF2, EIF2 alpha, EIF2A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 1 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit alpha, IF2A_HUMAN
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Alternative Produkte zum Anti-EIF2S1 Antikörper [PCRP-EIF2S1-1E2] (A248414)

Oben