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Anti-E2F6 Antikörper [PCRP-E2F6-1F8] (A254378)

Monoklonal [PCRP-E2F6-1F8] Maus Antikörper gegen E2F6 für Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-E2F6 Antibody [PCRP-E2F6-1F8]
Beschreibung
Mouse monoclonal [PCRP-E2F6-1F8] antibody to E2F6.
Spezifität
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
Anwendungen
Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human E2F6 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-E2F6-1F8
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
35 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-E2F6 Antibody [PCRP-E2F6-1F8] - BSA and Azide free (A251562).
Synonyme
E2F 6, E2F binding site modulating activity protein, E2F transcription factor 6, E2F transcription factor 6 isoform 1, E2F-6, E2F6_HUMAN, EMA, MGC111545, Transcription factor E2F6
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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