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Rekombinant Anti-E Cadherin Antikörper [rCDH1/1525] (A254008)

Monoklonal [rCDH1/1525] Maus Antikörper gegen E Cadherin für WB, IF und IHC-P.

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Empfohlene Produkte für Anti-E Cadherin Antikörper

Produktname
Anti-E Cadherin Antibody [rCDH1/1525] - BSA and Azide free
Beschreibung
Recombinant mouse monoclonal [rCDH1/1525] antibody to E Cadherin.
Spezifität
This antibody recognizes a protein of 120-80kDa, identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.
Anwendungen
WB, IF, IHC-P
Verdünnungen
WB: 1-2 µg/ml, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody does not cross react with Mouse or Rat.
Immunogen
Recombinant full-length human E Cadherin protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rCDH1/1525
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
120-80 kDa (mature) / 135 kDa (Precursor)
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-E Cadherin Antibody [rCDH1/1525] (A250828).
Synonyme
Arc 1, CADH1_HUMAN, Cadherin 1, cadherin 1 type 1 E-cadherin, Cadherin1, CAM 120/80, CD 234, CD 324, CD324, CD324 antigen, CDH1, CDHE, E-Cad/CTF3, E-cadherin, ECAD , Epithelial cadherin, epithelial calcium dependant adhesion protein, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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