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Anti-Dopamine Transporter Antikörper (A283965)

$645

Polyklonal Kaninchen Antikörper gegen Dopamine Transporter für WB und IHC-Fr.

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Dopamine Transporter Antibody
Beschreibung
Rabbit polyclonal antibody to Dopamine Transporter.
Spezifität
This antibody recognises an epitope within the C-terminal region of dopamine transporter (DAT), also known as solute carrier family 6.DAT is principally expressed in the presynaptic membrane of dopaminergic nerve terminals, where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availability of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine.The reuptake of dopamine by DAT is inhibited by psychostimulants such as cocaine and amphetamine.
Anwendungen
WB, IHC-Fr
Verdünnungen
IHC-Fr: 1:1,000, WB: 1:1,000
Reaktivität
Human, Monkey, Mouse
Immunogen
Synthetic peptide corresponding to the C-terminus of human dopamine transporter, conjugated to Keyhole Limpet Haemocyanin.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat

Unconjugated

Konzentration
Lot Specific
Molekulargewicht
Approximately 88 kDa in human caudate cell lysates.
Produktform
Liquid
Formulierung
Supplied in 10mM HEPES, pH 7.5, with 150mM NaCl, 0.01% BSA, 50% Glycerol, and 0.05% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Allgemeine Hinweise
Rabbit anti Human dopamine transporter antibody recognizes an epitope within the C-terminal region of dopamine transporter (DAT), also known as solute carrier family 6. DAT is principally expressed in the presynaptic membrane of dopaminergic nerve terminals, where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availability of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine. The reuptake of dopamine by DAT is inhibited by psychostimulants such as cocaine and amphetamine.
Synonyme
DA transporter, DAT, DAT 1, DAT1, Dopamine transporter 1, PKDYS, SC6A3_HUMAN, SLC6A3, Sodium dependent dopamine transporter, Sodium-dependent dopamine transporter, Solute carrier family 6 (neurotransmitter transporter dopamine), member 3, Solute carrier family 6 (neurotransmitter transporter), member 3, Solute carrier family 6 member 3, Variable number tandem repeat (VNTR)
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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