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Anti-Desmoglein 3 Antikörper [DSG3/2839] (A251561)

Monoklonal [DSG3/2839] Maus Antikörper gegen Desmoglein 3 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Desmoglein 3 Antibody [DSG3/2839] - BSA and Azide free
Beschreibung
Mouse monoclonal [DSG3/2839] antibody to Desmoglein 3.
Spezifität
This antibody recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 379-491, human DSG3 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
DSG3/2839
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
130 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Desmoglein 3 Antibody [DSG3/2839] (A248379).
Synonyme
130 kD pemphigus vulgaris antigen, 130 kDa pemphigus vulgaris antigen, Balding, Cadherin family member 6, CDHF 6, CDHF6, Desmoglein 3 precursor, Desmoglein-3, Desmoglein3, DKFZp686P23184, DSG 3, DSG3, DSG3_HUMAN, Pemphigus vulgaris antigen, PVA
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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