Anti-DAXX Antikörper [PCRP-DAXX-8C2] (A248319)

Anti-DAXX Antibody [PCRP-DAXX-8C2]

Mouse monoclonal [PCRP-DAXX-8C2] antibody to DAXX.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human DAXX protein.

Mouse

Monoclonal

PCRP-DAXX-8C2

IgG

Protein A/G chromatography.

200 µg/ml

81.37 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-DAXX Antibody [PCRP-DAXX-8C2] - BSA and Azide free (A251501).

, BING 2, BING2, CENP-C binding protein, DAP 6, DAP6, DAXX_HUMAN, Death associated protein 6, Death domain associated protein, Death domain associated protein 6, Death domain-associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, ETS1-associated protein 1, Fas binding protein, Fas death domain associated protein, Fas death domain-associated protein, hDaxx, MGC126245, MGC126246