Anti-Daxx Antikörper [PCRP-DAXX-6E11] (A316261)

Anti-Daxx Antibody [PCRP-DAXX-6E11] - BSA and Azide free

Mouse monoclonal [PCRP-DAXX-6E11] antibody to Daxx.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Flow Cytometry, IHC-P

HeLa or U87 cells. Ubiquitous tissue expression.

Flow Cytometry: 1-2 µg/million cells, IHC: 1-2 µg/ml

Human

Recombinant full-length human DAXX protein.

Mouse

Monoclonal

PCRP-DAXX-6E11

Unconjugated

Protein A/G chromatography.

1 mg/ml

81.37 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

, BING 2, BING2, CENP-C binding protein, DAP 6, DAP6, DAXX_HUMAN, Death associated protein 6, Death domain associated protein, Death domain associated protein 6, Death domain-associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, ETS1-associated protein 1, Fas binding protein, Fas death domain associated protein, Fas death domain-associated protein, hDaxx, MGC126245, MGC126246