Anti-Cytokeratin 6A Antibody [KRT6/3997R] - BSA and Azide free
Beschreibung
Recombinant rabbit monoclonal [KRT6/3997R] antibody to Cytokeratin 6A.
Spezifität
Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests.Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment corresponding to human Cytokeratin 6. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
KRT6/3997R
Isotyp
IgG
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
56 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Negative Tissue Control: Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain using Anti-Cytokeratin 6A Antibody [KRT6/3997R] at 2µg/ml in PBS for 30 minutes at room temperature.
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