This antibody recognises human I-TAC (Interferon-inducible T-cell alpha chemoattractant), otherwise known as CXCL11, a member of the CXC chemokine family, which signals through binding to CD183 (CXCR3), and is regulated by interferon gamma and beta.I-TAC is highly expressed by peripheral blood leucocytes, the pancreas and liver, and acts as a potent chemoattractant for IL-2 activated T cells, as well as a natural antagonist for CD195 (CCR5).

Anwendungen

WB, ELISA, IHC-P, Functional Assays

Verdünnungen

ELISA: 0.5 - 2 µg/ml, Functional Assays: 7.0 - 8.0 µg/ml, WB: 0.1 - 0.2 µg/ml

Reaktivität

Human

Immunogen

Recombinant human I-TAC.

Wirt

Rabbit

Klonalität

Polyclonal

Isotyp

IgG

Konjugat

Unconjugated

Konzentration

1 mg/ml after reconstitution.

Produktform

Lyophilized

Rekonstitution

Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Formulierung

Supplied in Phosphate Buffered Saline.

Lagerung

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Allgemeine Hinweise

Rabbit anti Human I-TAC antibody recognizes human I-TAC (Interferon-inducible T-cell alpha chemoattractant), otherwise known as CXCL11, a member of the CXC chemokine family, which signals through binding to CD183 (CXCR3), and is regulated by interferon gamma and beta.I-TAC is highly expressed by peripheral blood leucocytes, the pancreas and liver, and acts as a potent chemoattractant for IL-2 activated T cells, as well as a natural antagonist for CD195 (CCR5).

Synonyme

b R1, b-R1, Beta R1, Beta-R1, betaR1, C X C motif chemokine 11, C-X-C motif chemokine 11, Chemokine (C-X-C motif) ligand 11, Chemokine C-X-C motif ligand 11, CXC11, CXL11_HUMAN, H174, I TAC, I-TAC, Interferon gamma inducible protein 9, Interferon gamma-inducible protein 9, Interferon inducible T cell a chemoattractant I TAC, Interferon inducible T cell alpha chemoattractant, Interferon-inducible T-cell a chemoattractant I-TAC, Interferon-inducible T-cell alpha chemoattractant, IP 9, IP-9, IP9, ITAC, MGC102770 , SCYB11, SCYB9B, Small inducible cytokine B11, Small inducible cytokine subfamily B (Cys X Cys) member 11 , Small inducible cytokine subfamily B (Cys X Cys) member 9B, Small inducible cytokine subfamily B (Cys-X-Cys) member 11, Small inducible cytokine subfamily B (Cys-X-Cys) member 9B, Small inducible cytokine subfamily B, member 11, Small inducible cytokine subfamily B, member 9B, Small-inducible cytokine B11

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.