Recombinant rabbit monoclonal [CKBB/8840R] antibody to Creatine Kinase MB.
Spezifität
Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB.
Anwendungen
IHC-P
Positivkontrolle
SH-SY5Y or HEK-293 cells. Human cerebellum.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant human full-length CKB protein.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
CKBB/8840R
Isotyp
IgG
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
42 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.