This antibody recognises the carboxy-terminus of type VII collagen. Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components. Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain. Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin.

Anwendungen

IHC-Fr

Verdünnungen

IHC-Fr: 1:25 - 1:100

Reaktivität

Human

Kreuzreaktivität

This antibody does not cross react with Rat, Mouse, or Pig

Immunogen

Crude extract of skin.

Wirt

Mouse

Klonalität

Monoclonal

Klon

LH7.2

Isotyp

IgG1

Konjugat

Unconjugated

Reinigung

Protein A affinity chromatography of tissue culture supernatant.

Konzentration

1 mg/ml

Produktform

Liquid

Formulierung

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Lagerung

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Allgemeine Hinweise

Mouse anti Human collagen VII antibody, clone LH7.2 recognizes the carboxy-terminus of type VII collagen (Kirkham et al. 1989). Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components (Gammon et al. 1992). Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain.Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin (Watson et al. 2001).

Synonyme

Alpha 1 type VII collagen, CO7A1_HUMAN, Col7a1, Collagen alpha 1(VII) chain, Collagen alpha-1(VII) chain, Collagen type VII alpha 1, Collagen VII alpha 1 polypeptide, CollagenVII, EBD 1, EBD1, EBDCT, EBR 1, EBR1, LC collagen, Long chain collagen, Long-chain collagen

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.