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Anti-CFTR Antikörper [rCFTR/6476] (A277534)

Monoklonal [rCFTR/6476] Maus Antikörper gegen CFTR für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
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Email
orders@antibodies.com
Produktname
Anti-CFTR Antibody [rCFTR/6476]
Beschreibung
Mouse monoclonal [rCFTR/6476] antibody to CFTR.
Spezifität
This antibody recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 0.5-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 258-385, of human CFTR protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rCFTR/6476
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A chromatography.
Konzentration
200 µg/ml
Molekulargewicht
165-170 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CFTR Antibody [rCFTR/6476] - BSA and Azide free (A278122).
Synonyme
ABC 35, ABC35, ABCC 7, ABCC7, ATP binding cassette sub family C member 7, ATP Binding Cassette Superfamily C Member 7, ATP binding cassette transporter sub family C member 7, ATP-binding cassette sub-family C member 7, cAMP dependent chloride channel, cAMP-dependent chloride channel, CF, CFTR/MRP, CFTR_HUMAN, Channel conductance controlling ATPase, Channel conductance-controlling ATPase, Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C, member 7), Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7, Cystic Fibrosis Transmembrane Regulator, dJ760C5.1, MRP 7, MRP7, TNR CFTR
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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