Rabbit polyclonal antibody to Cdk6 (phospho Tyr24).
Spezifität
This antibody recognises cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6.
Anwendungen
WB, IHC-P
Verdünnungen
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000
Reaktivität
Human, Mouse
Immunogen
Phospho-specific peptide corresponding to residues surrounding Tyr24 of human Cdk6.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
Lot Specific
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Lagerung
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti Cdk6 (pTyr13) recognizes cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6 (Bertero et al. 2013).