Anti-CD59 Antibody [MEM-43] (A281151)

Anti-CD59 Antibody [MEM-43]

Mouse monoclonal [MEM-43] antibody to CD59.

This antibody recognises CD59, a glycosyl-phosphatidylinositol (GPI) anchored membrane protein also known as membrane attack complex inhibition factor. CD59 blocks the formation of the complement membrane attack complex (MAC) by binding of C8a and C9. CD59 is found on all types of leucocytes including platelets and is also expressed on many non-haematopoietic cells. The epitope recognized by Mouse anti Human CD59 antibody, clone MEM-43 is lost after reduction therefore, non-reducing conditions are required for western blotting techniques.

WB, IHC-P, IP, Flow Cytometry, ELISA, IHC-Fr, IF, Electron Microscopy

Flow Cytometry: 1:25 - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Human

Thymocytes and T lymphocytes.

Mouse

Monoclonal

MEM-43

IgG2a

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD59 antibody, clone MEM-43 recognizes CD59, a glycosyl-phosphatidylinositol (GPI) anchored membrane protein also known as membrane attack complex inhibition factor. CD59 blocks the formation of the complement membrane attack complex (MAC) by binding of C8a and C9. CD59 is found on all types of leucocytes including platelets and is also expressed on many non-haematopoietic cells. The epitope recognized by Mouse anti Human CD59 antibody, clone MEM-43 is lost after reduction therefore, non-reducing conditions are required for western blotting techniques.

1F5 antigen, 20 kDa homologous restriction factor, CD59 glycoprotein, HRF-20, HRF20, MAC-inhibitory protein, MAC-IP, MACIF, MEM43 antigen, Membrane attack complex inhibition factor, MIC11, MIN1, MIN2, MIN3, MSK21