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Anti-CD55 Antikörper [Bu14] (A279876)

$480

Monoklonal [Bu14] Maus Antikörper gegen CD55 für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-CD55 Antibody [Bu14]
Beschreibung
Mouse monoclonal [Bu14] antibody to CD55.
Spezifität
This antibody recognises human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway.The molecular weight of CD55 varies between ~50 and 100 kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid. CD55 acts as a ligand for CD97 and is an entry receptor for Echovirus and Coxsackie B virus. CD55 has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development.
Anwendungen
Flow Cytometry
Verdünnungen
Flow Cytometry: Neat - 1:200, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reaktivität
Human
Wirt
Mouse
Klonalität
Monoclonal
Klon
Bu14
Isotyp
IgG1
Konjugat

Unconjugated

Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Allgemeine Hinweise
Mouse anti Human CD55 antibody, clone Bu14 recognizes human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway.The molecular weight of CD55 varies between ~50 and 100 kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid (Medof et al. 1987).CD55 acts as a ligand for CD97 (Hamaan et al. 1998) and is an entry receptor for Echovirus (Bergelson et al. 1994) and Coxsackie B virus (Hafenstein et al. 2007). CD55 has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development (Visser et al. 2002).
Synonyme
CD 55, CD55 antigen, CD55 Cromer blood group system, CD55 molecule, CD55 molecule (Cromer blood group), CD55 molecule, decay accelerating factor for complement (Cromer blood group), Cd55a, Complement decay accelerating factor, Complement decay-accelerating factor, Complement decay-accelerating factor, GPI-anchored, CR, CROM, Cromer Blood Group antigen, Cromer blood group system, DAF, Daf-GPI, Daf1, DAF_HUMAN, Dcay accelerating factor for complement (CD55, Cromer blood group system), Decay accelarating factor 1, isoform CRA_a, Decay accelerating factor (GPI-form), Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF, TC
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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