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Anti-CD55 Antikörper [67] (PE) (A278753)

$515

Monoklonal [67] Maus Antikörper gegen CD55 (PE) für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-CD55 Antibody [67] (PE)
Beschreibung
Mouse monoclonal [67] antibody to CD55 (PE).
Spezifität
This antibody recognises the human CD55 cell surface antigen, a GPI linked molecule also known as decay accelerating factor (DAF). CD55 is expressed by a wide range of cell types.CD55 is the complement regulatory protein, decay accelerating factor (DAF). Human CD55 is a ~70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens.DAF has a wide distribution on cells in non-haematopoietic tissues, particularly epithelium and is found at the fetal-maternal interface in placenta (Holmes et al. 1990 and Yang et al. 2009). Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.
Anwendungen
Flow Cytometry
Verdünnungen
Flow Cytometry: Neat - 1:2, Use 10µl of the suggested working dilution to label 106 cells in 100&mul
Reaktivität
Human
Immunogen
K562 cell line.
Wirt
Mouse
Klonalität
Monoclonal
Klon
67
Isotyp
IgG1
Konjugat

PE

Excitation: 565nm, Emission: 578nm

Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
Reconstitution dependent.
Produktform
Lyophilized
Rekonstitution
Reconstitute with 1 ml of distilled water.
Formulierung
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Lagerung
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Mouse anti Human CD55 antibody, clone 67 recognizes the human CD55 cell surface antigen, a GPI linked molecule also known as decay accelerating factor (DAF). CD55 is expressed by a wide range of cell types.CD55 is the complement regulatory protein, decay accelerating factor (DAF) (Lublin and Atkinson 1989). Human CD55 is a ~70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens.DAF has a wide distribution on cells in non-haematopoietic tissues, particularly epithelium and is found at the fetal-maternal interface in placenta (Holmes et al. 1990 and Yang et al. 2009). Soluble forms of DAF are found, for example, in plasma, saliva and urine (Medof et al. 1987). The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.
Synonyme
CD 55, CD55 antigen, CD55 Cromer blood group system, CD55 molecule, CD55 molecule (Cromer blood group), CD55 molecule, decay accelerating factor for complement (Cromer blood group), Cd55a, Complement decay accelerating factor, Complement decay-accelerating factor, Complement decay-accelerating factor, GPI-anchored, CR, CROM, Cromer Blood Group antigen, Cromer blood group system, DAF, Daf-GPI, Daf1, DAF_HUMAN, Dcay accelerating factor for complement (CD55, Cromer blood group system), Decay accelarating factor 1, isoform CRA_a, Decay accelerating factor (GPI-form), Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF, TC
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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