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Anti-CD53 Antikörper [161-2] (A250738)

Monoklonal [161-2] Maus Antikörper gegen CD53 für Functional Studies, Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-CD53 Antibody [161-2]
Beschreibung
Mouse monoclonal [161-2] antibody to CD53.
Spezifität
This antibody recognizes a protein of 33-55kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This antibody recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Anwendungen
Functional Studies, Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody does not cross react with Baboon or Horse.
Immunogen
Stimulated human leukocytes.
Wirt
Mouse
Klonalität
Monoclonal
Klon
161-2
Isotyp
IgG2a
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
33-55 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD53 Antibody [161-2] - BSA and Azide free (A253918).
Synonyme
AI323659, Antigen MOX44 identified by monoclonal, CD 53, CD53 antigen, CD53 antigen, isoform CRA_b, CD53 glycoprotein, Cd53 molecule, CD53 tetraspan antigen, CD53_HUMAN, Cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44, Leukocyte surface antigen CD53, MOX 44, MOX44, OTTHUMP00000059505, Ox-44, OX44, RATOX44, Tetraspanin 25, Tetraspanin-25, Tetraspanin25, Transmembrane glycoprotein, TSPAN 25, Tspan-25, TSPAN25
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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