This antibody recognises an epitope encoded by exon v6 on the variant portion of murine CD44. CD44v6 has been identified along with ICAM-1 as a co-receptor for Met and in mammary epithelia appears to act at the primary Met co-receptor. Rat anti Mouse CD44v6, clone 9A4 has been used successfully for the identification of CD44v6 expressing cells by immunofluorescence , western blotting. Immunohistochemistry along with ELISA and flow cytometry.
Applications
WB, IHC-P, ELISA, IHC-Fr
Reactivity
Mouse
Immunogen
GST-CD44v6 fusion protein.
Host
Rat
Clonality
Monoclonal
Clone ID
9A4
Isotype
IgG1
Conjugate
Unconjugated
Concentration
500 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rat anti Mouse CD44v6, clone 9A4 recognizes an epitope encoded by exon v6 on the variant portion of murine CD44. CD44v6 has been identified along with ICAM-1 as a co-receptor for Met and in mammary epithelia appears to act at the primary Met co-receptor (Di-Cicco et al. 2015).Rat anti Mouse CD44v6, clone 9A4 has been used successfully for the identification of CD44v6 expressing cells by immunofluorescence (Di-Cicco et al. 2015), western blotting (Lo et al. 2012). Immunohistochemistry (Weilenga et al. 1999) along with ELISA and flow cytometry (Weiss et al. 1997).