Anti-CD3 Antibody [OKT3] - Low endotoxin, Azide free (A85522)

Anti-CD3 Antibody [OKT3] - Low endotoxin, Azide free

Mouse monoclonal [OKT3] antibody to CD3.

This antibody recognizes an extracellular epitope on CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart, and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.

Flow Cytometry, IHC-Fr, Functional Studies

FUNC: Counteracting both generation and function of effector T cells, Flow Cytometry: 1 µg/ml.

Human

Human PBMCs.

Mouse

Monoclonal

OKT3

IgG2a

Protein A chromatography.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

CD3d, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain, T3D