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Anti-CD11c Antikörper [ITGAX/1243] (A249073)

Monoklonal [ITGAX/1243] Maus Antikörper gegen CD11c für ELISA.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
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Email
orders@antibodies.com
Produktname
Anti-CD11c Antibody [ITGAX/1243]
Beschreibung
Mouse monoclonal [ITGAX/1243] antibody to CD11c.
Spezifität
This antibody recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Anwendungen
ELISA
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 637-827, of human ITGAX protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
ITGAX/1243
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
145 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD11c Antibody [ITGAX/1243] - BSA and Azide free (A252253).
Synonyme
95, 95 alpha chain, CD 11c, CD11 antigen like family member C, CD11 antigen-like family member C, CD11c antigen, Complement component 3 receptor 4 subunit, CR4, Integrin alpha X, Integrin alpha X chain, Integrin alpha-X, Integrin aX, Integrin subunit alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit, ITAX_HUMAN, ITGAX, Leu M5, LEU M5 alpha subunit, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150, Leukocyte adhesion receptor p150 95, Leukocyte surface antigen p150 95 alpha subunit, Leukocyte surface antigen p150 alpha subunit, Myeloid membrane antigen alpha subunit, p150, p150 95 integrin alpha chain, p150/95, SLEB6
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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