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Anti-CD11b Antikörper [OX-42] (FITC) (A281458)

$235

Monoklonal [OX-42] Maus Antikörper gegen CD11b (FITC) für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-CD11b Antibody [OX-42] (FITC)
Beschreibung
Mouse monoclonal [OX-42] antibody to CD11b (FITC).
Spezifität
This antibody recognises rat CD11b, also known as integrin alpha-M, the receptor for the iC3b component of complement. CD11b is a 1151 amino acid single pass type 1 transmembrane glycoprotein posessing a single vWFA domain and multiple FG-GAP repeats. CD11b is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglia in the brain. Mouse anti Rat CD11b, clone OX-42 is reported to inhibit complement mediated rosettes as well as inhibit myelin binding and uptake.
Anwendungen
Flow Cytometry
Verdünnungen
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Reaktivität
Rat
Immunogen
Resident rat peritoneal macrophages.
Wirt
Mouse
Klonalität
Monoclonal
Klon
OX-42
Isotyp
IgG2a
Konjugat

FITC

Excitation: 490nm, Emission: 525nm

Reinigung
Protein G affinity chromatography of tissue culture supernatant.
Konzentration
100 µg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Lagerung
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Allgemeine Hinweise
Mouse anti Rat CD11b, clone OX-42 recognizes rat CD11b, also known as integrin alpha-M, the receptor for the iC3b component of complement. CD11b is a 1151 amino acid single pass type 1 transmembrane glycoprotein posessing a single vWFA domain and multiple FG-GAP repeats. CD11b is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglia in the brain (Robinson et al.1986).Mouse anti Rat CD11b, clone OX-42 is reported to inhibit complement mediated rosettes (Robinson et al.1986) as well as inhibit myelin binding and uptake (van der Laan et al.1996).
Synonyme
antigen CD11b (p170), Antigen CD11b p170, CD11 antigen like family member B, CD11 antigen-like family member B, CD11b/CD18, CD49d, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, Complement Component Receptor 3 Alpha, Complement receptor type 3, alpha subunit, CR 3 alpha chain, CR 3 alpha chain (CR3A), CR-3 alpha chain, CR3, CR3A, F730045J24Rik, Integrin Alpha M, Integrin alpha M chain, Integrin alpha-M, Integrin beta 2 alpha subunit, Integrin subunit alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITAM_HUMAN, ITGAM, Leukocyte adhesion receptor MO1, Ly-40, MAC 1, Mac-1a, MAC1, Mac1, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MGC117044, Mo1, alpha subunit, MO1A, Neutrophil adherence receptor, Neutrophil adherence receptor alpha M subunit, SLEB6
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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