This antibody recognises calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Anwendungen

Verdünnungen

WB: 1:500 - 1:2,000

Reaktivität

Human, Mouse, Rat

Immunogen

Phospho-specific peptide corresponding to residues surrounding Thr286 of human CaMK II alpha.

Wirt

Rabbit

Klonalität

Polyclonal

Isotyp

IgG

Konjugat

Unconjugated

Konzentration

Lot Specific

Produktform

Liquid

Formulierung

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Lagerung

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Allgemeine Hinweise

Rabbit anti CaMK II alpha (pThr286) antibody recognizes calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Synonyme

Alpha CaMKII, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha B subunit, Calcium/calmodulin dependent protein kinase type II alpha chain, Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase II alpha, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type IIA, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMK II alpha subunit, CaMK-II subunit alpha, Camk2a, CAMKA, CaMKII, CaMKIINalpha, EC 2.7.11.17, KCC2A_HUMAN, KIAA0968, MGC123320, MGC139375, MGC155201, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.