This antibody recognizes human blood group A including weak variants A₃, A_X, A₃B, A_XB. The specifity of this antibody was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood.

Anwendungen

AGG

Reaktivität

Human

Immunogen

Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.

Wirt

Mouse

Klonalität

Monoclonal

Klon

HE-195

Isotyp

IgM

Konjugat

Unconjugated

Reinigung

Concentrated by membrane ultrafiltration.

Reinheit

Tissue culture supernatant.

Produktform

Liquid

Formulierung

Supplied as an aliquot of concentrated tissue culture supernatant.

Lagerung

Shipped at 4°C. Store at 2-8°C. Do not freeze!

Isotyp-Kontrollantikörper

Mouse IgM [PRF-03] (A86761)

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktreferenzen für diesen Klon (1)

Publikation anzeigen

Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine.

Verweise: Anti-Blood Group A Antigen Antibody [HE-195] (ab2522)

Abstrakt:

Six different hybridoma cell lines were obtained producing IgM monoclonal antibodies (MAbs) against human blood group A antigen. All these MAbs agglutinate the A1, A1B and A2 erythrocytes, while only one of them agglutinates the A2B erythrocytes. The agglutination activity of 3 of these MAbs is inhibited by N-acetyl-D-galactosamine (D-GalNAc). Dissociation constants of complexes of these MAbs with D-GalNAc are approximately 2.2 X 10(-3) mol/l.

Publikation anzeigen