Anti-Bcl6 Antibody [PCRP-GCM2-1B3] (A314489)

Anti-Bcl6 Antibody [PCRP-GCM2-1B3]

Mouse monoclonal [PCRP-GCM2-1B3] antibody to Bcl6.

Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Flow Cytometry, IF

HeLa or MCF-7 cells.

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

This antibody is predicted to cross react with Mouse and Rat.

Recombinant human GCM2 protein.

Mouse

Monoclonal

PCRP-GCM2-1B3

Protein A/G chromatography.

200 µg/ml

56.61 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, BCL-5, BCL-6, BCL5, LAZ3, Protein LAZ-3, ZBTB27, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51, ZNF51